1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; 2-hydroxyethanethiol / acetone / 3 h / 20 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 6 h / 0 °C 3.1: titanium(IV) isopropylate; trimethylsilylazide / benzene / 2 h / 5 - 20 °C / Inert atmosphere 3.2: 1 h 4.1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere 5.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.75 h / -78 °C / Inert atmosphere 5.2: 0.5 h / -78 °C / Inert atmosphere 5.3: 0.5 h 6.1: pyridine; dihydrogen peroxide / dichloromethane / 0.5 h / 20 °C 7.1: triphenylphosphine / toluene / 3 h / Reflux 8.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 0 - 20 °C 9.1: boron trifluoride diethyl etherate / 3 h / -20 °C / Inert atmosphere 10.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C 10.2: 4 °C View Scheme

Multi-step reaction with 2 steps 1: potassium carbonate / 5 h / 20 °C2: triphenylphosphine; diethylazodicarboxylate / toluene / 6 h / -20 °C / Inert atmosphere  

Multi-step reaction with 5 steps 1.1: lithium hydroxide hydrate / tetrahydrofuran; water / 26 h / 20 °C1.2: pH 2 / Acidic aq. solution2.1: sodium hydrogencarbonate / water2.2: 20 °C / Darkness3.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 6 h / Reflux4.1: potassium carbonate / 5 h / 20 °C5.1: triphenylphosphine; diethylazodicarboxylate / toluene / 6 h / -20 °C / Inert atmosphere  

Multi-step reaction with 2 steps 1: 1,8-diazabicyclo[5.4.0]undec-7-ene; 2-hydroxyethanethiol / acetone / 3 h / 20 °C2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 6 h / 0 °C