5(R)-5-{(叔丁基二甲基甲硅烷基氧基)甲基}吡咯烷-2-酮合成路线 （共 5 条）
反应条件
1H-imidazole in dichloromethane T=20°C; 4 h;
参考文献
Lin, Qi-Xian; Ho, Tse-Lok
Tetrahedron, 2013 , vol. 69, # 14 p. 2996 - 3001
反应条件
1: H2O / 63 h / Heating 2: SOCl2 / 48 h / Ambient temperature; pH=0 3: 58 percent / NaBH4 / propan-2-ol / 20 h / Ambient temperature 4: 99 percent / imidazole / dimethylformamide / 24 h / Ambient temperature View Scheme
参考文献
Ackermann, Jean; Matthes, Michael; Tamm, Christoph
Helvetica Chimica Acta, 1990 , vol. 73, # 1 p. 122 - 132
反应条件
1: 58 percent / NaBH4 / propan-2-ol / 20 h / Ambient temperature 2: 99 percent / imidazole / dimethylformamide / 24 h / Ambient temperature View Scheme
参考文献
Ackermann, Jean; Matthes, Michael; Tamm, Christoph
Helvetica Chimica Acta, 1990 , vol. 73, # 1 p. 122 - 132
反应条件
1: SOCl2 / 48 h / Ambient temperature; pH=0 2: 58 percent / NaBH4 / propan-2-ol / 20 h / Ambient temperature 3: 99 percent / imidazole / dimethylformamide / 24 h / Ambient temperature View Scheme
参考文献
Ackermann, Jean; Matthes, Michael; Tamm, Christoph
Helvetica Chimica Acta, 1990 , vol. 73, # 1 p. 122 - 132
反应条件
1: 84 percent / DMAP, NEt3 / CH2Cl2 / 24 h / Ambient temperature 2: 57 percent / TsOH / methanol / 6 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 73, # 1 p. 122 - 132
