palladium on activated charcoal; hydrogen in methanol Ambient temperature;

With  acetic acid T=85°C; 2 h;   

Multi-step reaction with 4 steps 1: 93 percent / toluene-p-sulfonic acid / dimethylformamide / 1.5 h / 70 °C / 12 Torr2: 72 percent / mercury(II) cyanide, molecular sieve 3 Angstroem / acetonitrile / 24 h / Ambient temperature3: 95 percent / KOH / dioxane4: 92 percent / aq. 90percent acetic acid / 2 h / 85 °C