3-(2-甲基丙基)-5-苯基-2(1h)-吡嗪酮合成路线 （共 4 条）
反应条件
ammonium acetate in ethanol 3.5 h; Heating;
参考文献
Roberts, David A.; Bradbury, Robert H.; Brown, David; Faull, Alan; Griffiths, David; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2326 - 2334
反应条件
1: 1.) 1,3-dicyclohexylcarbodiimide (DCC), 2.) 1-hydroxybenzotriazole hydrate (HOBT) / CH2Cl2 2: 67 percent / ammonium acetate / ethanol / 3.5 h / Heating View Scheme
参考文献
Bradbury, Robert H.; Griffiths, David; Rivett, Janet E.
Heterocycles, 1990 , vol. 31, # 9 p. 1647 - 1653
反应条件
1: 1.) 1,3-dicyclohexylcarbodiimide (DCC), 2.) 1-hydroxybenzotriazole hydrate (HOBT) / CH2Cl2 2: 67 percent / ammonium acetate / ethanol / 3.5 h / Heating View Scheme
参考文献
Bradbury, Robert H.; Griffiths, David; Rivett, Janet E.
Heterocycles, 1990 , vol. 31, # 9 p. 1647 - 1653
反应条件
sodium hydroxide in methanol 1.) -40 deg C, 2 h, 2.) RT, 1 h;
参考文献
Bradbury, Robert H.; Griffiths, David; Rivett, Janet E.
Heterocycles, 1990 , vol. 31, # 9 p. 1647 - 1653
