2,3-二氨基-6-溴吡啶合成路线 （共 6 条）
反应条件
hydrogenchloride; iron in ethanol; water T=20°C; 2 h; Heating / reflux;
参考文献
US6348474 B1, ;
Page column 45 ;
反应条件
1: With trifluoroacetic acid T=85°C; 2 h; 2: With sodium hydrogencarbonate in water
参考文献
WO2010/127152 A2, ;
Page/Page column 107-108 ;
WO 2010/127152 A2
反应条件
hydrogenchloride in ethanol (220 ml)-water; water
反应条件
1: 4.5 h; Reflux; 2: With sodium hydroxide
参考文献
US2010/222345 A1, ;
Page/Page column 91 ;
反应条件
potassium carbonate in dichloromethane; acetic acid
参考文献
Fujisawa Pharmaceutical Co. Ltd.
Patent: US6573274 B1, 2003 ;
反应条件
in acetic acid 29 h; Heating / reflux;
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US6348474 B1, 2002 ;
Location in patent: Page column 45 ;
