反应条件
1: LAH / diethyl ether / 1 h
2: 1.) methanesulfonyl chloride, Et3N, 2.) LiBr / 1.) THF, RT, 2 h, 2.) THF, RT, 16 h
3: 1.) lithium cyclohexylisopropylamide, 2.) HMP / 1.) -78 deg C, 20 min, 2.) RT, overnight
4: 64 percent / p-toluenesulfonic acid / 16 h / 60 °C
View Scheme
参考文献
Sonnet, Philip E.; Hayes, Douglas
Journal of the American Oil Chemists' Society, 1995 , vol. 72, # 9 p. 1069 - 1071
