乙基N-(1H-吡咯-2-基羰基)-beta-丙氨酸酯合成路线 （共 6 条）
反应条件
triethylamine in acetonitrile T=20°C; 48 h;
参考文献
Papeo, Gianluca; Posteri, Helena; Borghi, Daniela; Varasi, Mario
Organic Letters, 2005 , vol. 7, # 25 p. 5641 - 5644
反应条件
1: pyrrole; trichloromethyl chloroformate With 2,3-dimethyl aniline in toluene 2: amino propionic acid ethyl ester in dichloromethane
参考文献
Portevin, Bernard; Golsteyn, Roy M.; Pierre, Alain; De Nanteuil, Guillaume
Tetrahedron Letters, 2003 , vol. 44, # 52 p. 9263 - 9265
反应条件
triethylamine; dicyclohexyl-carbodiimide in dichloromethane 15 h;
参考文献
Kasum, Bruno; Prager, Rolf H.; Tsopelas, Chris
Australian Journal of Chemistry, 1990 , vol. 43, # 2 p. 355 - 365
反应条件
sodium hydroxide T=60 - 70°C; 1 h;
参考文献
Kasum, Bruno; Prager, Rolf H.; Tsopelas, Chris
Australian Journal of Chemistry, 1990 , vol. 43, # 2 p. 355 - 365
反应条件
1: With sodium hydroxide in ethanol
2: With PPA; phosphorus pentoxide
参考文献
Portevin, Bernard; Golsteyn, Roy M.; Pierre, Alain; De Nanteuil, Guillaume
Tetrahedron Letters, 2003 , vol. 44, # 52 p. 9263 - 9265
反应条件
1: 67 percent / N-bromosuccinimide / methanol; tetrahydrofuran / 0 - 20 °C
2: 92 percent / NaOH / H2O / 18 h / 20 °C
3: oxalyl chloride / 1,2-dichloro-ethane; dimethylformamide / 0.33 h / 20 °C
4: 53 percent / aluminium trichloride; molecular sieves 4 Angstroem / 1,2-dichloro-ethane; dimethylformamide / 20 °C
View Scheme
参考文献
Papeo, Gianluca; Posteri, Helena; Borghi, Daniela; Varasi, Mario
Organic Letters, 2005 , vol. 7, # 25 p. 5641 - 5644
