[(1R)-2-氨基-1-苄基-2-氧乙基]氨基甲酸叔丁酯合成路线 (共 6 条)
反应条件
pyridine; di-tert-butyl dicarbonate; NH4HCO3 in acetonitrile 4-16 h;
参考文献
Tetrahedron Letters, , vol. 36, # 39 p. 7115 - 7118
反应条件
ammonium hydroxide in methanol; water T=20°C; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 77, # 23 p. 10596 - 10616
参考文献
Journal of Organic Chemistry, , vol. 75, # 19 p. 6614 - 6624
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 24 p. 7355 - 7358
反应条件
hydrogenchloride in 1,4-dioxane 0.5 h; Ambient temperature;
参考文献
Schoen, Istvan; Rill, Attila
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 12 p. 3360 - 3373
反应条件
TEA; trifluoroacetic anhydride in tetrahydrofuran
T=20°C; 0.5 h;
参考文献
Donkor, Isaac O.; Han, Jie; Zheng, Xiaozhang
Journal of Medicinal Chemistry, 2004 , vol. 47, # 1 p. 72 - 79