1.1: cesium fluoride; toluene-4-sulfonic acid; Me2PhSiBpin / N,N-dimethyl-formamide / 3 h / 100 °C / 3800.26 Torr / |Autoclave 1.2: 0.17 h / 0 °C 2.1: ozone; oxygen / methanol; dichloromethane / 0.5 h / -78 °C 3.1: [RhCl(PPh3)2] / acetonitrile / 2 h / |Reflux View Scheme

1.1: cesium fluoride; toluene-4-sulfonic acid; Me2PhSiBpin / N,N-dimethyl-formamide / 3 h / 100 °C / 3800.26 Torr / |Autoclave 1.2: 0.17 h / 0 °C 2.1: ozone; oxygen / methanol; dichloromethane / 0.5 h / -78 °C 3.1: sodium tetrahydroborate; methanol / 2 h / -20 °C View Scheme

Multi-step reaction with 2 steps 1.1: cesium fluoride; toluene-4-sulfonic acid / N,N-dimethyl-formamide / 3 h / 20 °C / |Inert atmosphere2.1: cesium fluoride / N,N-dimethyl-formamide / 3 h / 100 °C / 3800.26 Torr2.2: 0.17 h / 0 °C