1: α-acetylaminoacrylic acid With triphenylphosphine; hydroxymethyl polystyrene resin; diethylazodicarboxylate in tetrahydrofuran; toluene T=20°C; 24 h; 2: 2-(trifluoromethanesulfonyl)oxy-bromobenzene With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; N,N-dicyclohexylmethylamine; [(t-Bu)3PH]BF4 in ethylene glycol dimethyl ether Heck reaction; 3: sodium methylate in tetrahydrofuran; methanol T=20°C; 12 h;

tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethanol; toluene Heating;

sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether Heating;