5-(4-乙氧基苯基)-(9ci)-1H-吡唑-3-胺合成路线 （共 3 条）
反应条件
hydrazine in tetrahydrofuran; n-butyllithium; ethanol; acetonitrile
参考文献
Allergan, Inc.
Patent: US6559173 B1, 2003 ;
US 6559173 B1
反应条件
hydrazine hydrate in ethanol 2 h; Heating; Yield given;
参考文献
Larsen, Scott D.; Spilman, Charles H.; Bell, Frank P.; Dinh, Dac M.; Martinborough, Esther; Wilson, Gracella J.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1721 - 1727
反应条件
1: C2H5ONa / toluene / 24 h / 108 °C 2: H2N-NH2*H2O / aq. ethanol / 2 h / Heating View Scheme
参考文献
Larsen, Scott D.; Spilman, Charles H.; Bell, Frank P.; Dinh, Dac M.; Martinborough, Esther; Wilson, Gracella J.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1721 - 1727
