N-芴甲氧羰基-脯氨酰-脯氨酸合成路线 （共 7 条）
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 6 h;
参考文献
Dai, Zhi; Ye, Guozhong; Pittman Jr., Charles U.; Li, Tingyu
Chirality, 2012 , vol. 24, # 4 p. 329 - 338
反应条件
sodium hydroxide in methanol
参考文献
Gayathri; Gopi; Suresh Babu
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1998 , vol. 37, # 2 p. 151 - 154
反应条件
1: 75 percent / 1-hydroxybenzotriazole potassium salt / CH2Cl2 / 0.5 h / Ambient temperature 2: 76 percent / NaOH / methanol View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 37, # 2 p. 151 - 154
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0.17 h / 0 °C 1.2: 14 h / 0 - 20 °C 2.1: piperidine / acetonitrile / 1 h / 20 °C 3.1: benzotriazol-1-ol / dichloromethane / 0.17 h / 0 °C 3.2: 0 - 20 °C 4.1: trifluoroacetic acid / dichloromethane / 6 h / 20 °C View Scheme
参考文献
Chirality, , vol. 24, # 4 p. 329 - 338
反应条件
1.1: benzotriazol-1-ol / dichloromethane / 0.17 h / 0 °C 1.2: 0 - 20 °C 2.1: trifluoroacetic acid / dichloromethane / 6 h / 20 °C View Scheme
参考文献
Chirality, , vol. 24, # 4 p. 329 - 338
反应条件
1.1: piperidine / acetonitrile / 1 h / 20 °C 2.1: benzotriazol-1-ol / dichloromethane / 0.17 h / 0 °C 2.2: 0 - 20 °C 3.1: trifluoroacetic acid / dichloromethane / 6 h / 20 °C View Scheme
参考文献
Chirality, , vol. 24, # 4 p. 329 - 338
反应条件
piperidine in N,N-dimethyl-formamide 0.5 h;
参考文献
Xiang, Dao Feng; Patskovsky, Yury; Xu, Chengfu; Fedorov, Alexander A.; Fedorov, Elena V.; Sisco, Abby A.; Sauder, J. Michael; Burley, Stephen K.; Almo, Steven C.; Raushel, Frank M.
Biochemistry, 2010 , vol. 49, # 31 p. 6791 - 6803
