3-氨基-4-羟基喹啉盐酸盐合成路线 (共 3 条)
反应条件
1: aqueous HCl; aqueous NaNO2 2: aqueous acetic acid View Scheme
参考文献
Sues et al.
Justus Liebigs Annalen der Chemie, 1953 , vol. 583, p. 150,155
反应条件
hydrogenchloride; sodium nitrite
参考文献
Sues et al.
Justus Liebigs Annalen der Chemie, 1953 , vol. 583, p. 150,155
反应条件
1: 3-amino-quinolin-4-ol; hydrochloride; N,N-dimethyl-formamide With trichlorophosphate in acetonitrile
T=20°C; 21 h;
2: isobutylamine in acetonitrile
T=120°C; 3 h; Product distribution / selectivity;
参考文献
3M INNOVATIVE PROPERTIES COMPANY
Patent: WO2007/35935 A1, 2007 ;
Location in patent: Page/Page column 90-91 ;