(4R)-4-羟基-1-三苯甲基-L-脯氨酸甲酯合成路线 （共 15 条）
反应条件
triethylamine in chloroform T=0°C;
参考文献
Demange, Luc; Menez, Andre; Dugave, Christophe
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1169 - 1172
反应条件
triethylamine in dichloromethane T=20°C; 2 h;
参考文献
Kehat, Tzofit; Portnoy, Moshe
Chemical Communications, 2007 , # 27 p. 2823 - 2825
反应条件
triethylamine in chloroform T=0 - 20°C; 27 h; Inert atmosphere;
参考文献
Orliac, Aurelie; Routier, Julie; Burgat Charvillon, Fabienne; Sauer, Wolfgang H. B.; Bombrun, Agnes; Kulkarni, Santosh S.; Gomez Pardo, Domingo; Cossy, Janine
Chemistry - A European Journal, 2014 , vol. 20, # 13 p. 3813 - 3824
反应条件
1: 83 percent / conc. HCl / Ambient temperature 2: 0.75 g / triethylamine / CH2Cl2 / 0.08 h / Ambient temperature View Scheme
参考文献
Orliac, Aurelie; Routier, Julie; Burgat Charvillon, Fabienne; Sauer, Wolfgang H. B.; Bombrun, Agnes; Kulkarni, Santosh S.; Gomez Pardo, Domingo; Cossy, Janine
Chemistry - A European Journal, 2014 , vol. 20, # 13 p. 3813 - 3824
反应条件
1: 1.) PPh3, DEAD, PhCO2H; 2.) KOH / 1.) toluene; 2.) MeOH 2: HCO2H / 1,2-dichloro-ethane 3: Et3N / CH2Cl2 / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 10 p. 1169 - 1172
反应条件
1: 1.) PPh3, DEAD, PhCO2H; 2.) KOH / 1.) toluene; 2.) MeOH 2: 63 percent / DAST / CH2Cl2 / -78 deg C to r.t. 3: 99 percent / LiOH / acetonitrile; H2O / Ambient temperature 4: TFA / CH2Cl2 View Scheme
参考文献
Demange, Luc; Menez, Andre; Dugave, Christophe
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1169 - 1172
反应条件
1: 1.) PPh3, DEAD, PhCO2H; 2.) KOH / 1.) toluene; 2.) MeOH 2: HCO2H / 1,2-dichloro-ethane 3: Et3N / CH2Cl2 / Ambient temperature View Scheme
参考文献
Demange, Luc; Menez, Andre; Dugave, Christophe
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1169 - 1172
反应条件
1: 1.) PPh3, DEAD, PhCO2H; 2.) KOH / 1.) toluene; 2.) MeOH 2: HCO2H / 1,2-dichloro-ethane 3: Et3N / CH2Cl2 / Ambient temperature View Scheme
参考文献
Demange, Luc; Menez, Andre; Dugave, Christophe
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1169 - 1172
反应条件
1: 1.) PPh3, DEAD, PhCO2H; 2.) KOH / 1.) toluene; 2.) MeOH 2: 63 percent / DAST / CH2Cl2 / -78 deg C to r.t. 3: 99 percent / LiOH / acetonitrile; H2O / Ambient temperature 4: TFA / CH2Cl2 View Scheme
参考文献
Demange, Luc; Menez, Andre; Dugave, Christophe
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1169 - 1172
反应条件
4,4'-diaminostilbene-2,2'-disulfonic acid in dichloromethane -78 deg C to r.t.;
参考文献
Demange, Luc; Menez, Andre; Dugave, Christophe
Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1169 - 1172
