1: 70 percent / 40percent aq. MeNH2 / 72 h / Ambient temperature 2: 63 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating 3: 83 percent / 72 h / Ambient temperature View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3647881', constants.ctx, '0')">sodium</a> <br />&nbsp;1) THF, 0 deg C, 2 h, 2) -75 deg C, 18 h, THF;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;