1-Boc-5-氨基-1H-吲唑合成路线 （共 4 条）
反应条件
in methanol; palladium; ethyl acetate
参考文献
Ko, Soo S.; Pruitt, James R.; Wacker, Dean A.; Batt, Douglas G.
Patent: US2003/32654 A1, 2003 ;
US 20030032654 A1
反应条件
hydrogen; palladium 10 on activated carbon in ethanol 23 h;
参考文献
MYRIAD GENETICS, INC.
Patent: WO2006/135383 A2, 2006 ;
Location in patent: Page/Page column 123-124 ;
反应条件
1: With 4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane 17 h; 2: With citric acid; sodium chloride in dichloromethane; water
参考文献
MYRIAD GENETICS, INC.
Patent: WO2006/135383 A2, 2006 ;
Location in patent: Page/Page column 123 ;
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / tetrahydrofuran / 16 h / 30 °C 2: hydrogen / palladium on activated charcoal / tetrahydrofuran / 16 h / 40 °C / 2585.81 Torr View Scheme
参考文献
WO2012/146724 A2, ;
WO 2012/146724 A2
