4-氨基-1-[(2R,4S,5R)-4-羟基-5-(羟基甲基)四氢呋喃-2-基]-5-(甲氧基甲基)嘧啶-2-酮合成路线 (共 3 条)
反应条件
ammonia in methanol 4 h; Ambient temperature;
参考文献
Jia; Tourigny; Delbaere; Stuart; Gupta
Canadian Journal of Chemistry, 1990 , vol. 68, # 6 p. 836 - 841
参考文献
University of Saskatchewan
Patent: US4990499 A1, 1991 ;
反应条件
1: 70 percent / pyridine / 18 h / Ambient temperature 2: POCl3, triethylamine / acetonitrile / 1.5 h / Ambient temperature 3: 84 percent / NH3 / dioxane / 18 h / Ambient temperature; pressure bottle 4: 74 percent / NH3 / methanol / 4 h / Ambient temperature View Scheme
参考文献
Jia; Tourigny; Delbaere; Stuart; Gupta
Canadian Journal of Chemistry, 1990 , vol. 68, # 6 p. 836 - 841