1: 88 percent / pyridine / acetonitrile / 1 h / 0 °C 2: 43 percent / t-BuOOH, D-(-)-DIPT, Ti(O-i-Pr)4, molecular sieves 4 Angstroem / CH2Cl2 / 16 h / -21 °C 3: t-BuOOH, Ti(O-i-Pr)4, L-(+)-DIPT, molecular sieves 4 Angstroem / CH2Cl2 / -21 °C 4: PPh3, diethyl azodicarboxylate / tetrahydrofuran / 1 h / 0 °C 5: 1N NaOH / methanol / 1 h / 0 °C 6: 1) Bu3SnLi, 2) I2 / 1) THF, 0 deg C, 3h, 2) Et2O, 0 deg C 7: imidazole / dimethylformamide / Ambient temperature 8: 1) disiamylborane, 2) LiOH / 2) Pd(PPh3)4 / 1) THF, 0 deg C, 1h, 2) 40 degC, 12h 9: 79 percent / n-Bu4NF / tetrahydrofuran / 18 h / Ambient temperature View Scheme