4-(4-氟苯氧基)苯甲酸合成路线 (共 4 条)
反应条件
1: With molecular sieve; copper diacetate; triethylamine in dichloromethane T=20°C; 16 h; 2: With hydrogenchloride; lithium hydroxide in 1,4-dioxane; water T=20°C; 18 h;
参考文献
Walker, Daniel Patrick; Piotrowski, David W.; Jacobsen, Eric Jon; Acker, Brad A.; Myers, Jason K.; Groppi JR., Vincent E.
Patent: US2003/236279 A1, 2003 ;
Location in patent: Page 34 ;
反应条件
hydrogenchloride; triethanolamine; copper diacetate; silica gel in 1,4-dioxane; dichloromethane
参考文献
Myers, Jason K.; Groppi JR., Vincent E.; Piotrowski, David W.
Patent: US2002/40035 A1, 2002 ;
反应条件
hydrogenchloride; LiOH; triethanolamine; copper diacetate; silica gel in 1,4-dioxane; 3-fluorobenzene boronic acid; dichloromethane
参考文献
Wishka, Donn G.; Myers, Jason K.; Groppi JR., Vincent E.
Patent: US2003/69296 A1, 2003 ;
反应条件
potassium permanganate
参考文献
Pharmazie, , vol. 54, # 4 p. 260 - 262