1: pyridine / 24 h / Ambient temperature 2: 85 percent / trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane / 44 h / 50 °C 3: 32 percent / 1,2-dichloro-ethane / 24 h / Ambient temperature 4: 88 percent / H2 / Pd-C / methanol / 1 h / Ambient temperature 5: 2.) M NaOH, 3.) M LiOH / 1.) pyridine, 37 deg C, 24 h; 2.) water, room temp., 1 h View Scheme