反应条件
1: 79 percent / H2 / 10percent Pd/C / acetic acid / 2 h / 1216 Torr / Ambient temperature
2: 74 percent / conc. HCl, H2 / 10percent Pd/C / methanol / 4.5 h / 1216 Torr / Ambient temperature
3: 1.) NaH / 1.) DME, RT, 20 min, 2.) RT, 1 h
4: 32 percent / 30percent aq. H2O2 / CH2Cl2 / 2.5 h / Ambient temperature
5: 1.) NaH / 1.) DME, RT, 30 min, 2.) DME, reflux, 1 h
View Scheme
参考文献
Matsuo; Arase
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 12 p. 2091 - 2094
