5-三氟甲基吡唑-3-甲酸合成路线 （共 2 条）
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C; 20 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 63 ;
WO 2006/023750 A2
反应条件
1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU in dichloromethane
T=20°C; 0.75 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 64 ;
WO 2006/023750 A2
