2-三氟甲硫基-1,1’-联苯合成路线 （共 20 条）
反应条件
sodium hydride in N,N-dimethyl-formamide 1.) ice bath temp., 10 min; r.t., 20 min, 2.) 50 deg C, 3 h;
参考文献
Umemoto, Teruo; Ishihara, Sumi
Journal of Fluorine Chemistry, 1999 , vol. 98, # 1 p. 75 - 81
反应条件
1: 1-bromo-2-phenylbenzene With Pd(CH2SiMe3)2(cod); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in toluene T=80°C; 0.0166667 h; Inert atmosphere; 2: silver (I) trifluoro methyl sulfide With Ph(Et)3NI in toluene T=80°C; 2 h; Inert atmosphere;
参考文献
Teverovskiy, Georgiy; Surry, David S.; Buchwald, Stephen L.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 32 p. 7312 - 7314
反应条件
triethylamine tris(hydrogen fluoride) T=180°C; 9 h;
参考文献
Umemoto, Teruo; Ishihara, Sumi
Journal of Fluorine Chemistry, 1999 , vol. 98, # 1 p. 75 - 81
反应条件
sodium hydride 1.) DMF, 2.) DMF, irradiation, 2 h; Yield given. Multistep reaction;
参考文献
Sagami Chemical Research Center
Patent: US5066795 A1, 1991 ;
反应条件
in N,N-dimethyl-formamide T=0°C; Irradiation;
参考文献
Umemoto; Ishihara
Tetrahedron Letters, 1990 , vol. 31, # 25 p. 3579 - 3582
反应条件
1: 0.58 h / 264 - 282 °C 2: NaOH / methanol / 12 h / Heating 3: LiH / dimethylformamide / -60 °C 4: SbF3 / 2 h / 150 - 160 °C View Scheme
参考文献
Umemoto, Teruo; Ishihara, Sumi
Journal of Fluorine Chemistry, 1999 , vol. 98, # 1 p. 75 - 81
反应条件
1: NaOH / methanol / 12 h / Heating 2: LiH / dimethylformamide / -60 °C 3: SbF3 / 2 h / 150 - 160 °C View Scheme
参考文献
Umemoto, Teruo; Ishihara, Sumi
Journal of Fluorine Chemistry, 1999 , vol. 98, # 1 p. 75 - 81
反应条件
1: 86 percent / dimethylformamide / 20 - 80 °C 2: 0.58 h / 264 - 282 °C 3: NaOH / methanol / 12 h / Heating 4: LiH / dimethylformamide / -60 °C 5: SbF3 / 2 h / 150 - 160 °C View Scheme
参考文献
Umemoto, Teruo; Ishihara, Sumi
Journal of Fluorine Chemistry, 1999 , vol. 98, # 1 p. 75 - 81
反应条件
1: LiH / dimethylformamide / -60 °C 2: SbF3 / 2 h / 150 - 160 °C View Scheme
参考文献
Umemoto, Teruo; Ishihara, Sumi
Journal of Fluorine Chemistry, 1998 , vol. 92, # 2 p. 181 - 187
反应条件
SbF3 T=150 - 160°C; 2 h; Yield given;
参考文献
Umemoto, Teruo; Ishihara, Sumi
Journal of Fluorine Chemistry, 1999 , vol. 98, # 1 p. 75 - 81
