1: With trifluoroacetic acid in dichloromethane T=0 - 23°C; 2 h; 2: With sodium hydrogencarbonate in water pH=~ 8;

<b>Multi-step reaction with 3 steps<br /> </b>1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 &deg;C / Inert atmosphere<br />1.2: 5 h / 23 &deg;C<br />2.1: hydrazine hydrate; anhydrous iron chloride / methanol / 90 &deg;C<br />3.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; pyridine / 48 h / 23 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 &deg;C / Inert atmosphere<br />1.2: 5 h / 23 &deg;C<br />2.1: hydrazine hydrate; anhydrous iron chloride / methanol / 90 &deg;C<br />3.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; pyridine / 48 h / 23 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: tetrahydrofuran / 18 h / 20 &deg;C / Inert atmosphere<br />2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; pyridine / 48 h / 23 &deg;C<br /> <br /> &nbsp;