1-溴-2-(乙基磺酰基)苯合成路线 （共 3 条）
反应条件
chromium(VI) oxide; periodic acid in acetonitrile T=0 - 20°C;
参考文献
MERCK SHARP and DOHME CORP.; BUNGARD, Christopher, James; PERKINS, James, J.; MANIKOWSKI, Jesse, J.; DE LEON, Pablo; MEISSNER, Robert, S.
Patent: WO2011/53574 A1, 2011 ;
Location in patent: Page/Page column 29-30 ;
反应条件
1: 2-bromobenzenesulphonyl chloride With sodium hydrogencarbonate; sodium sulfite in water T=20 - 100°C; 3 h; Inert atmosphereSchlenk technique; 2: ethyl iodide With tetrabutylammomium bromide in water T=70°C; Inert atmosphereSchlenk technique;
参考文献
Bheeter, Charles Beromeo; Jin, Rongwei; Bera, Jitendra K.; Doucet, Henri
RSC Advances, 2013 , vol. 3, # 17 p. 5987 - 5996
反应条件
1: caesium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C 2: chromium(VI) oxide; periodic acid / acetonitrile / 0 - 20 °C View Scheme
参考文献
MERCK SHARP and DOHME CORP.; BUNGARD, Christopher, James; PERKINS, James, J.; MANIKOWSKI, Jesse, J.; DE LEON, Pablo; MEISSNER, Robert, S.
Patent: WO2011/53574 A1, 2011 ;
