caesium carbonate; palladium dichloride in N,N-dimethyl-formamide T=110°C; 19 h; Inert atmosphere;

1: 88 percent / conc. H2SO4 / 4 h / Ambient temperature 2: 49 percent 3: 29 percent / isoamyl nitrite / CH2Cl2; tetrahydrofuran / 1.5 h / Heating 4: 30 percent / conc. HCl / methanol / 16 h / Heating View Scheme

1: 29 percent / isoamyl nitrite / CH2Cl2; tetrahydrofuran / 1.5 h / Heating 2: 30 percent / conc. HCl / methanol / 16 h / Heating View Scheme

1: 49 percent 2: 29 percent / isoamyl nitrite / CH2Cl2; tetrahydrofuran / 1.5 h / Heating 3: 30 percent / conc. HCl / methanol / 16 h / Heating View Scheme

hydrogenchloride in methanol 16 h; Heating;