1: LAH / tetrahydrofuran / 1.) reflux, 5 h, 2.) r.t. 2: CH2Cl2 / 0.5 h / Ambient temperature 3: 1.) NaH / 1.) THF, r.t., 30 min, 2.) r.t., 2 h 4: 70 percent / LAH, AlCl3 / tetrahydrofuran / 1.5 h / Heating View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587194', constants.ctx, '0')">iodine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1696894', constants.ctx, '0')">diethyl ether</a> <br />&nbsp;Ambient temperatureIrradiation;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 96 percent / aq. ammonia / methanol / 48 h / Ambient temperature<br />2: 40 percent / iodine / diethyl ether / Ambient temperature; Irradiation<br /> <br /> &nbsp;