反应条件
1: 1.) Na2S2O4, n-tetrabutylammonium bromide, 2.) KOH / 1.) aq. THF
2: 87 percent / TFAA, TFA / 12 h / 60 °C
3: 95 percent / Et3SiH / trifluoroacetic acid / 6 h / 25 °C
4: 81 percent / HBr / acetic acid / 9 h / 45 - 50 °C
5: 100 percent / dioxane; H2O / 10 h / Heating
6: 73 percent / aq. KOH / methanol / 22 h / Heating
7: 63 percent / PPA / 1.5 h / 60 - 70 °C
8: 1.) NBS, dibenzoyl peroxide, 2.) H2O / 1.) CCl4, reflux, 4.5 h
9: 74 percent / PCC, Celite / CH2Cl2 / 3 h / 25 °C
10: 69 percent / AlCl3 / CH2Cl2 / 4 h / 55 °C
11: 1.) Me3SiI, 2.) MeOH / 1.) CDCl3, 25 deg C, 27 h
12: p-TsOH / benzene / 5 h / Heating
View Scheme
参考文献
Joshi; Jiang; Rho; Pelletier
Journal of Organic Chemistry, 1994 , vol. 59, # 26 p. 8220 - 8232
