7-(3,5-二甲基异噁唑-4-基)-8-甲氧基-1-((R)-1-(吡啶-2-基)乙基)-1H-咪唑并[4,5-c]喹啉-2(3H)-酮合成路线 （共 12 条）
反应条件
1: potassium hydroxide; [bis(acetoxy)iodo]benzene / methanol / Cooling with ice 2: Chiralpak IA column / n-heptane; ethanol / Resolution of racemate View Scheme
反应条件
1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 120 °C 2: [bis(acetoxy)iodo]benzene; potassium hydroxide / methanol / 1.33 h / Cooling with ice View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 8 p. 2963 - 2967
