N-[(1S)-1-氰基乙基]-氨基甲酸叔丁酯合成路线 （共 6 条）
反应条件
pyridine; trifluoroacetic anhydride in tetrahydrofuran T=-10 - 0°C; 2 h;
参考文献
Sureshbabu, Vommina V.; Naik, Shankar A.; Nagendra
Synthetic Communications, 2009 , vol. 39, # 3 p. 395 - 406
反应条件
1: With 3 A molecular sieve; hydroxylamine hydrochloride; 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane T=20°C; 10 h; 2: With ethyl phosphorodichloridate in dichloromethane T=20°C; 5 h; Further stages.;
参考文献
Zhu, Jia-Liang; Lee, Fa-Yen; Wu, Jen-Dar; Kuo, Chun-Wei; Shia, Kak-Shan
Synlett, 2007 , # 8 p. 1317 - 1319
反应条件
sodium hydroxide in 1,4-dioxane; water 0.5 h; Ambient temperature;
参考文献
Kohrt, Arne; Hartke, Klaus
Liebigs Annalen der Chemie, 1992 , # 6 p. 595 - 606
反应条件
N-(o-trifluoromethylbenzyl)quininium bromide; potassium carbonate in toluene T=-20°C; 42 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 71, # 26 p. 9869 - 9872
反应条件
1: aq. NaOH / dioxane / 0 °C 2: ethyl chloroformate; triethylamine; ammonia(g) / CH2Cl2 / -10 °C 3: cyanuric chloride / dimethylformamide / 0.5 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 48, # 8 p. 1465 - 1468
反应条件
1: ethyl chloroformate; triethylamine; ammonia(g) / CH2Cl2 / -10 °C 2: cyanuric chloride / dimethylformamide / 0.5 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 48, # 8 p. 1465 - 1468
