(R)-9-羟基利司哌酮合成路线 (共 14 条)
反应条件
tetra-(n-butyl)ammonium iodide; diisopropylamine in methanol T=45°C; 48 h;
参考文献
Xu, Weichu; Wright, George E.; Yanachkova, Milka; Yanachkov, Ivan B.
Letters in Organic Chemistry, 2014 , vol. 11, # 6 p. 470 - 473
反应条件
acetic acid; palladium monocarbide in water
反应条件
sodium borohydride in methanol; dichloromethane
反应条件
sodium carbonate in methanol; 3-(2-chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; dichloromethane; water
反应条件
sodium hydroxide; potassium iodide; sodium carbonate; acetic acid in water; acetonitrile
反应条件
1: acetic acid / palladium monocarbide 2: sodium borohydride / dichloromethane; methanol View Scheme
反应条件
1: hydrogenchloride; hydrogen; trichlorophosphate / toluene; cyclohexane; acetic acid 2: sodium borohydride / dichloromethane; methanol View Scheme
反应条件
1: hydrogenchloride; hydrogen; trichlorophosphate / toluene; cyclohexane; acetic acid 2: sodium borohydride / dichloromethane; methanol View Scheme
反应条件
1: sodium hydroxide / water 2: sodium borohydride / dichloromethane; methanol View Scheme