3-(苄氧基)-2-羟基丙酸合成路线 （共 9 条）
反应条件
1: 70 percent / H+ 2: 83 percent / Ph3P, DEAD 3: 90 percent / LiAlH4 4: pyridine View Scheme
参考文献
Witt, P. De; Misiti, D.; Zappia, G.
Tetrahedron Letters, 1989 , vol. 30, # 40 p. 5505 - 5506
反应条件
hydrogenchloride in methanol T=20°C; 18 h;
参考文献
Tetrahedron Asymmetry, , vol. 19, # 14 p. 1689 - 1697
反应条件
sulfuric acid 16 h; Reflux;
参考文献
WO2012/142671 A1, ;
Page/Page column 35; 36 ;
反应条件
hydrogenchloride; trimethyl orthoformate in methanol T=20°C; 19.5 h; Large scale;
参考文献
Organic Process Research and Development, , vol. 7, # 4 p. 521 - 532
参考文献
Tetrahedron Letters, , vol. 30, # 40 p. 5505 - 5506
反应条件
1: 70 percent / H+ 2: LiAlH4 / tetrahydrofuran 3: pyridine 4: sodium methoxide View Scheme
参考文献
Witt, P. De; Misiti, D.; Zappia, G.
Tetrahedron Letters, 1989 , vol. 30, # 40 p. 5505 - 5506
反应条件
1: 70 percent / H+ 2: LiAlH4 / tetrahydrofuran 3: pyridine View Scheme
参考文献
Witt, P. De; Misiti, D.; Zappia, G.
Tetrahedron Letters, 1989 , vol. 30, # 40 p. 5505 - 5506
反应条件
1: 70 percent / H+ 2: LiAlH4 / tetrahydrofuran 3: 83 percent / Et3N / CH2Cl2 4: pyridine 5: TBAF / tetrahydrofuran View Scheme
参考文献
Witt, P. De; Misiti, D.; Zappia, G.
Tetrahedron Letters, 1989 , vol. 30, # 40 p. 5505 - 5506
反应条件
1: 70 percent / H+
2: LiAlH4 / tetrahydrofuran
3: 83 percent / Et3N / CH2Cl2
4: pyridine
5: TBAF / tetrahydrofuran
View Scheme
参考文献
Witt, P. De; Misiti, D.; Zappia, G.
Tetrahedron Letters, 1989 , vol. 30, # 40 p. 5505 - 5506
