(R)3-氧代环戊烷羧酸合成路线 （共 11 条）
反应条件
cation exchange resin 24 h; Heating;
参考文献
Sung, Sun-Young; Frahm, August Wilhelm
Archiv der Pharmazie, 1996 , vol. 329, # 6 p. 291 - 300
反应条件
ozone in methanol
T=-78°C; 0.5 h;
参考文献
Yu, Xiao-Qiang; Shirai, Tomohiko; Yamamoto, Yasunori; Miyaura, Norio
Chemistry - An Asian Journal, 2011 , vol. 6, # 3 p. 932 - 937
反应条件
1: 64 percent / tetrahydrofuran / -78 °C
2: 69 percent / TBAF / tetrahydrofuran
3: 1.) O3, 2.) DMS
4: CrO3, aq. H2SO4
View Scheme
参考文献
Lassaletta, Jose-Maria; Fernandez, Rosario; Martin-Zamora, Eloisa; Diez, Elena
Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 7002 - 7003
反应条件
(-)-Brucine in water
Reflux;
参考文献
Ausmees, Kerti; Selyutina, Anastasia; Kuett, Kristel; Lippur, Kristin; Pehk, Tonis; Lopp, Margus; Zusinaite, Eva; Merits, Andres; Kanger, Tonis
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 11 p. 897 - 907
反应条件
hydrogenchloride; zinc(II) chloride in methanol
4 h; Heating;
参考文献
De Raadt; Griengl; Petsch; Plachota; Schoo; Weber; Braunegg; Kopper; Kreiner; Zeiser
Tetrahedron Asymmetry, 1996 , vol. 7, # 2 p. 473 - 490
反应条件
chromium(VI) oxide; sulfuric acid
Yield given;
参考文献
Lassaletta, Jose-Maria; Fernandez, Rosario; Martin-Zamora, Eloisa; Diez, Elena
Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 7002 - 7003
反应条件
Syntrophobacter fumaroxidans nitrilase NIT278; water in aq. phosphate buffer; water
T=37°C; pH=7.3; 48 h; Enzymatic reaction; pH-valueTemperatureSolvent; Overall yield = 74 percent; Overall yield = 14 mg; enantiospecific reaction;
参考文献
Vergne-Vaxelaire, Carine; Bordier, Franck; Fossey, Aurelie; Besnard-Gonnet, Marielle; Debard, Adrien; Mariage, Aline; Pellouin, Virginie; Perret, Alain; Petit, Jean-Louis; Stam, Mark; Salanoubat, Marcel; Weissenbach, Jean; De Berardinis, Veronique; Zaparucha, Anne
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 9 p. 1763 - 1779
反应条件
1: 70 percent / polyphosphate ethyl ester / CH2Cl2 / Heating
2: Cunninghamella blakesleeana, medium E
3: 43 percent / aq. HCl, ZnCl2 / methanol / 4 h / Heating
View Scheme
参考文献
De Raadt; Griengl; Petsch; Plachota; Schoo; Weber; Braunegg; Kopper; Kreiner; Zeiser
Tetrahedron Asymmetry, 1996 , vol. 7, # 2 p. 473 - 490
反应条件
1: Cunninghamella blakesleeana, medium E
2: 43 percent / aq. HCl, ZnCl2 / methanol / 4 h / Heating
View Scheme
参考文献
De Raadt; Griengl; Petsch; Plachota; Schoo; Weber; Braunegg; Kopper; Kreiner; Zeiser
Tetrahedron Asymmetry, 1996 , vol. 7, # 2 p. 473 - 490
反应条件
Yield given. Multistep reaction;
参考文献
Diez; Fernandez; Gasch; Lassaletta; Llera; Martin-Zamora; Vazquez
Journal of Organic Chemistry, 1997 , vol. 62, # 15 p. 5144 - 5155
