sodium cyanide in dimethyl sulfoxide T=160 - 170°C; 12 h; Yield given;

1: sulfur, 5percent Pd/C / 2 h / 190 - 200 °C 2: NaCN / dimethylsulfoxide / 12 h / 160 - 170 °C View Scheme

1: 1.) BF3*Et2O, 2.) pyridine, POCl3 / 1.) a) 60 deg C, 2 h, b) 90 deg C, 2 h, 2.) heating 2: sulfur, 5percent Pd/C / 2 h / 190 - 200 °C 3: NaCN / dimethylsulfoxide / 12 h / 160 - 170 °C View Scheme