(Z)-7-[(1R,2R,3R,5S)-3,5-二羟基-2-[(E)-3-氧代-5-苯基戊-1-烯基]环戊基]庚-5-烯酸丙-2-基酯合成路线 (共 5 条)
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane 24 h; Ambient temperature;
参考文献
Resul, Bahram; Stjernschantz, Johan; No, Kiyo; Liljebris, Charlotta; Selen, Goeran; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 2 p. 243 - 248
反应条件
1: 80 percent / DBU / acetone / 10 h / Ambient temperature 2: 76 percent / DDQ / dioxane / 24 h / Ambient temperature View Scheme
参考文献
Resul, Bahram; Stjernschantz, Johan; No, Kiyo; Liljebris, Charlotta; Selen, Goeran; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 2 p. 243 - 248
反应条件
aluminium trichloride; 3 A molecular sieve; dihydrogen peroxide; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate; lithium chloride; 3,4,5-trimethoxyphenylboronic acid Yield given. Multistep reaction;
参考文献
Liljebris, Charlotta; Nilsson, Bjoern M.; Resul, Bahram; Hacksell, Uli
Journal of Organic Chemistry, 1996 , vol. 61, # 12 p. 4028 - 4034
反应条件
sodium tetrahydroborate; cerium(III) chloride in methanol; dichloromethane 0.5 h;
参考文献
Liljebris, Charlotta; Nilsson, Bjoern M.; Resul, Bahram; Hacksell, Uli
Journal of Organic Chemistry, 1996 , vol. 61, # 12 p. 4028 - 4034
反应条件
sodium tetrahydroborate; cerium(III) chloride in methanol; dichloromethane 0.5 h;
参考文献
Liljebris, Charlotta; Nilsson, Bjoern M.; Resul, Bahram; Hacksell, Uli
Journal of Organic Chemistry, 1996 , vol. 61, # 12 p. 4028 - 4034