1-(4-甲氧基-联苯-4-基)-乙酮合成路线 （共 91 条）
反应条件
triphenyl phosphite; K3PO4*3H2O; Ipr.HCl; palladium diacetate in tert-butyl alcohol
T=80°C; 6 h; Inert atmosphere;
参考文献
Chen, Xiaofeng; Ke, Haihua; Chen, Yao; Guan, Changwei; Zou, Gang
Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7572 - 7578
反应条件
bis-triphenylphosphine-palladium(II) chloride; tetrabutyl-ammonium chloride in tetrahydrofuran; N-dodecane
T=20°C; 18 h; Inert atmosphere; Reagent/catalyst;
参考文献
Hansmann, Max M.; Pernpointner, Markus; Doepp, Rene; Hashmi, A. Stephen K.
Chemistry - A European Journal, 2013 , vol. 19, # 45 p. 15290 - 15303
反应条件
morpholine; potassium phosphate; palladium diacetate in tert-butyl alcohol
T=80°C; Suzuki-Miyaura Coupling; 14 h; Inert atmosphere;
参考文献
Abe, Taichi; Mino, Takashi; Watanabe, Kohei; Yagishita, Fumitoshi; Sakamoto, Masami
European Journal of Organic Chemistry, 2014 , vol. 2014, # 18 p. 3909 - 3916
反应条件
triphenyl-arsane; lithium chloride; tris-(dibenzylideneacetone)dipalladium(0) in various solvent(s)
T=80°C; 70 h;
参考文献
Farina, Vittorio; Krishnan, Bala; Marshall, Daniel R.; Roth, Gregory P.
Journal of Organic Chemistry, 1993 , vol. 58, # 20 p. 5434 - 5444
反应条件
1,3-bis-(diphenylphosphino)propane; potassium carbonate; nickel dichloride in 1,4-dioxane
T=100°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Zhao, Yu-Long; Li, You; Li, Yu; Gao, Lian-Xun; Han, Fu-She
Chemistry - A European Journal, 2010 , vol. 16, # 17 p. 4991 - 4994
反应条件
1: 4-hydroxy-acetophenone With potassium phosphate; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate in 1,4-dioxane
T=100°C; 3 h; Inert atmosphere;
2: (4-methoxyphenyl)-boronic acid With [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane
T=100 - 110°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Chen, Guo-Jun; Huang, Jie; Gao, Lian-Xun; Han, Fu-She
Chemistry - A European Journal, 2011 , vol. 17, # 14 p. 4038 - 4042
反应条件
1: 4-aminoacetophenone With tert.-butylnitrite; boron trifluoride diethyl etherate in methanol
T=0°C; 0.5 h; Schlenk technique;
2: (4-methoxyphenyl)-boronic acid in methanol
T=0 - 60°C; 5 h; Schlenk technique;
参考文献
Zong, Yan; Hu, Jiefeng; Sun, Peipei; Jiang, Xiaoqing
Synlett, 2012 , vol. 23, # 16 art. no. ST-2012-W0506-L, p. 2393 - 2396
反应条件
1: para-iodoanisole With lithium chloride in N,N-dimethyl-formamide
T=80°C;
2: 4'-iodoacetophenone With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide
T=100°C; 5 h; Inert atmosphere;
参考文献
Papoian, Vardan; Minehan, Thomas
Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7376 - 7379
反应条件
palladium diacetate
T=100°C; Stille cross-coupling; 15 h; Ionic liquid;
参考文献
Louaisil, Nicolas; Pham, Phuoc Dien; Boeda, Fabien; Faye, Djibril; Castanet, Anne-Sophie; Legoupy, Stephanie
European Journal of Organic Chemistry, 2011 , # 1 p. 143 - 149
反应条件
Br(1-)*C20H23BrN5O6Pd(1+); sodium hydroxide in water
T=150°C; Hiyama coupling; 2 h; Sealed tube;
参考文献
Ines, Blanca; Moure, Maria Jesus; SanMartin, Raul; Herrero, Maria Teresa; Moreno, Isabel; Dominguez, Esther
Arkivoc, 2011 , vol. 2011, # 3 p. 191 - 199
