1-(4-甲氧基-联苯-4-基)-乙酮合成路线 （共 91 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; silver(l) oxide in tetrahydrofuran
T=70°C; Hiyama-type coupling; 18 h;
参考文献
Napier, Spencer; Marcuccio, Sebastian M.; Tye, Heather; Whittaker, Mark
Tetrahedron Letters, 2008 , vol. 49, # 24 p. 3939 - 3942
反应条件
palladium diacetate; triphenylphosphine in toluene
T=100°C; Suzuki coupling; 18 h;
参考文献
Ng, Ka-Ho; Zhou, Zhongyuan; Yu, Wing-Yiu
Organic Letters, 2012 , vol. 14, # 1 p. 272 - 275
反应条件
bis-triphenylphosphine-palladium(II) chloride; lithium chloride in tetrahydrofuran; N,N-dimethyl-formamide
T=80°C; 22 h;
参考文献
Curran, Dennis P.; Hoshino, Masahide
Journal of Organic Chemistry, 1996 , vol. 61, # 19 p. 6480 - 6481
反应条件
tetrabutylammomium bromide; potassium carbonate; quasi polymeric 4-pyridine-aldoxime Pd(II)-catalyst
T=120°C; Suzuki-Miyaura reaction; 0.333333 h; microwave irradiation;
参考文献
Solodenko, Wladimir; Schoen, Uwe; Messinger, Josef; Glinschert, Anja; Kirschning, Andreas
Synlett, 2004 , # 10 p. 1699 - 1702
反应条件
{[(PhCH2O)2P(CH3)2CHNCH(CH3)2]2PdCl2}; sodium acetate in 1-methyl-pyrrolidin-2-one; water
T=140°C; Suzuki Coupling; 24 h;
参考文献
Guo, Mengping; Wu, Xiaochun; Ge, Junying; Zhu, Zhiyong
Asian Journal of Chemistry, 2013 , vol. 25, # 13 p. 7251 - 7253
反应条件
1: N-acetyl-4-aminoacetophenone With boron trifluoride-methanol in methanol
T=65°C; Inert atmosphere;
2: With tert.-butylnitrite in methanol
T=0°C; 1 h; Inert atmosphere;
3: 4-MeOC4H6BF3K With palladium diacetate in methanol
T=20°C; Suzuki Coupling; 12.25 h; Inert atmosphere;
参考文献
Schmidt, Bernd; Berger, Rene
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 2-3 p. 463 - 476
反应条件
1: NaOH
2: AlCl3 / CS2
View Scheme
参考文献
Prajapati
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2001 , vol. 364, p. 769 - 777
反应条件
1.1: 73 percent / diethyl ether / 0 - 20 °C
2.1: TBAF / tetrahydrofuran
2.2: 73 percent / TBAF; (t-Bu)3P / [(allyl)PdCl]2 / tetrahydrofuran / 1 h / Heating
View Scheme
参考文献
Denmark, Scott E.; Wu, Zhicai
Organic Letters, 1999 , vol. 1, # 9 p. 1495 - 1498
反应条件
1: 69 percent / diethyl ether
2: 92 percent / silver(I) oxide / [Pd(PPh3)4] / tetrahydrofuran / 7 h / 60 °C
View Scheme
参考文献
Hirabayashi, Kazunori; Kondo, Tatsuhiro; Toriyama, Fumihiko; Nishihara, Yasushi; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 3 p. 749 - 750
反应条件
bis(η3-allyl-μ-chloropalladium(II)); 1,4-di(diphenylphosphino)-butane; potassium hydroxide in water; tert-butyl alcohol
T=90°C; 16 h;
参考文献
Boehner, Christine M.; Frye, Elizabeth C.; O'Connell, Kieron M. G.; Galloway, Warren R. J. D.; Sore, Hannah F.; Dominguez, Patricia Garcia; Norton, David; Hulcoop, David G.; Owen, Martin; Turner, Gillian; Crawford, Claire; Horsley, Helen; Spring, David R.
Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13230 - 13239
