3-氯-4-甲基苯并[B]噻吩合成路线 (共 2 条)
反应条件
copper in quinoline T=150°C; 3 h; Product distribution / selectivity;
参考文献
Teijin Pharma Limited
Patent: EP1947096 A1, 2008 ;
Location in patent: Page/Page column 13-14 ;
反应条件
1: Cl2 (gas) / CCl4 / 3 h / Ambient temperature 2: n-BuLi / diethyl ether; hexane / 1 h / 0 °C View Scheme
参考文献
Nussbaumer, Peter; Petranyi, Gabor; Stuetz, Anton
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 65 - 73