2-(3,4-二羟基苯基)-2-羟基-乙醛合成路线 （共 3 条）
反应条件
1: With pyridinium p-toluenesulfonate in methanol T=20°C; 4 h; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; 3 h;
参考文献
Narayanan, Jayan; Hayakawa, Yoshio; Fan, Junfa; Kirk, Kenneth L.
Bioorganic Chemistry, 2003 , vol. 31, # 2 p. 191 - 197
反应条件
1.1: conc. H2SO4 / Heating 2.1: pyridinium p-tosylate / CH2Cl2 / 1 h 3.1: 85 percent / KHMDS; 2-sulfonyloxaziridine / tetrahydrofuran; toluene / 0.33 h / -78 °C 4.1: 91 percent / pyridinium p-toluenesulfonate / CH2Cl2 / 20 °C 5.1: 93 percent / DIBALH / toluene; CH2Cl2 / 2 h / -78 °C 6.1: pyridinium p-tosylate / methanol / 4 h / 20 °C 6.2: 50 percent / 3M HCl / tetrahydrofuran; H2O / 3 h / 20 °C View Scheme
参考文献
Narayanan, Jayan; Hayakawa, Yoshio; Fan, Junfa; Kirk, Kenneth L.
Bioorganic Chemistry, 2003 , vol. 31, # 2 p. 191 - 197
反应条件
1.1: pyridinium p-tosylate / CH2Cl2 / 1 h 2.1: 85 percent / KHMDS; 2-sulfonyloxaziridine / tetrahydrofuran; toluene / 0.33 h / -78 °C 3.1: 91 percent / pyridinium p-toluenesulfonate / CH2Cl2 / 20 °C 4.1: 93 percent / DIBALH / toluene; CH2Cl2 / 2 h / -78 °C 5.1: pyridinium p-tosylate / methanol / 4 h / 20 °C 5.2: 50 percent / 3M HCl / tetrahydrofuran; H2O / 3 h / 20 °C View Scheme
参考文献
Narayanan, Jayan; Hayakawa, Yoshio; Fan, Junfa; Kirk, Kenneth L.
Bioorganic Chemistry, 2003 , vol. 31, # 2 p. 191 - 197
