1,4-脱水-2-脱氧-3-O-[(叔丁基)二苯基硅]-D-赤式-戊-1-烯糖醇合成路线 （共 13 条）
反应条件
ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane 4 h; Heating;
参考文献
Cameron, Melissa A.; Cush, Sarah B.; Hammer, Robert P.
Journal of Organic Chemistry, 1997 , vol. 62, # 26 p. 9065 - 9069
反应条件
potassium carbonate in methanol 0.166667 h;
参考文献
Benner, Steven Albert
Patent: US7741294 B1, 2010 ;
Location in patent: Page/Page column 17 ;
反应条件
1.1: 92 percent / imidazole / dimethylformamide / 12 h / 20 °C 2.1: 80 percent / para-toluenesulfonic acid / CH2Cl2; methanol / 0.5 h / cooling 3.1: ammonia sulfate / various solvent(s) / 2 h / 80 °C 3.2: 70 percent / K2CO3 / methanol / 0.5 h / cooling View Scheme
参考文献
Lan, Tao; McLaughlin, Larry W.
Bioorganic Chemistry, 2001 , vol. 29, # 4 p. 198 - 210
反应条件
1.1: 85 percent / pyridine / 2 h / 20 °C 2.1: 92 percent / imidazole / dimethylformamide / 12 h / 20 °C 3.1: 80 percent / para-toluenesulfonic acid / CH2Cl2; methanol / 0.5 h / cooling 4.1: ammonia sulfate / various solvent(s) / 2 h / 80 °C 4.2: 70 percent / K2CO3 / methanol / 0.5 h / cooling View Scheme
参考文献
Lan, Tao; McLaughlin, Larry W.
Bioorganic Chemistry, 2001 , vol. 29, # 4 p. 198 - 210
反应条件
1.1: 80 percent / para-toluenesulfonic acid / CH2Cl2; methanol / 0.5 h / cooling 2.1: ammonia sulfate / various solvent(s) / 2 h / 80 °C 2.2: 70 percent / K2CO3 / methanol / 0.5 h / cooling View Scheme
参考文献
Lan, Tao; McLaughlin, Larry W.
Bioorganic Chemistry, 2001 , vol. 29, # 4 p. 198 - 210
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether Ambient temperature;
参考文献
Walker II; Chen; Wise; Townsend
Journal of Organic Chemistry, 1996 , vol. 61, # 6 p. 2219 - 2221
反应条件
1: imidazole / dimethylformamide 2: NH3 / methanol 3: 79 percent / HMDS, (NH4)2SO4 / 4 h / Heating View Scheme
参考文献
Walker II; Chen; Wise; Townsend
Journal of Organic Chemistry, 1996 , vol. 61, # 6 p. 2219 - 2221
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
Coleman, Robert S.; Madaras, Mihaela L.
Journal of Organic Chemistry, 1998 , vol. 63, # 16 p. 5700 - 5703
反应条件
1: imidazole 2: n-Bu4NF / tetrahydrofuran View Scheme
参考文献
Coleman, Robert S.; Madaras, Mihaela L.
Journal of Organic Chemistry, 1998 , vol. 63, # 16 p. 5700 - 5703
反应条件
1: NH3 / methanol 2: 79 percent / HMDS, (NH4)2SO4 / 4 h / Heating View Scheme
参考文献
Cameron, Melissa A.; Cush, Sarah B.; Hammer, Robert P.
Journal of Organic Chemistry, 1997 , vol. 62, # 26 p. 9065 - 9069
