1-(氨基甲基)-3,4-二氢-3-苯基-1H-2-苯并吡喃-5,6-二醇盐酸盐合成路线 （共 8 条）
反应条件
1: 1.) n-BuLi / 1.) THF 2: pyridinium chlorochromate (PCC) 3: 75 percent / (-)-B-chlorodiisopinocampheyborane 4: BF3*Et2O 5: LiN3 / dimethylformamide 6: lithium aluminum hydride (LAH) / diethyl ether 7: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
反应条件
1: 75 percent / (-)-B-chlorodiisopinocampheyborane 2: BF3*Et2O 3: LiN3 / dimethylformamide 4: lithium aluminum hydride (LAH) / diethyl ether 5: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
反应条件
1: pyridinium chlorochromate (PCC) 2: 75 percent / (-)-B-chlorodiisopinocampheyborane 3: BF3*Et2O 4: LiN3 / dimethylformamide 5: lithium aluminum hydride (LAH) / diethyl ether 6: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
反应条件
1: 1.) n-BuLi / 1.) THF 2: pyridinium chlorochromate (PCC) 3: 75 percent / (-)-B-chlorodiisopinocampheyborane 4: BF3*Et2O 5: LiN3 / dimethylformamide 6: lithium aluminum hydride (LAH) / diethyl ether 7: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
反应条件
hydrogenchloride in ethanol
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
反应条件
1: BF3*Et2O 2: LiN3 / dimethylformamide 3: lithium aluminum hydride (LAH) / diethyl ether 4: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
反应条件
1: BF3*OEt2 2: LiN3 / dimethylformamide 3: lithium aluminum hydride (LAH) / diethyl ether 4: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
反应条件
1: LiN3 / dimethylformamide 2: lithium aluminum hydride (LAH) / diethyl ether 3: HCl / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 11 p. 2948 - 2950
