1: With 4-(N,N-dimethlyamino)pyridine in dichloromethane T=20°C; 2 h; Inert atmosphere; 2: With hydrogenchloride in water

sodium hydroxide; glutaryl-7-aminocephalosporanic acid acylase in water T=25°C; pH=8.0; Enzymatic reaction; Enzyme kinetics;

1: With 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=20°C; Inert atmosphere; 2: With immobilized Candida antarctica Lipase B; water in hexane T=30°C; pH=6.5; 24 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;

lipase from candida antartica in aq. phosphate buffer T=30°C; pH=6.5; 24 h;

glutaryl acylase in methanol; water T=25°C; pH=7.0; 8 h; Title compound not separated from byproducts;

1: With 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=20°C; Inert atmosphere; 2: With immobilized Candida antarctica Lipase B; water in hexane T=30°C; pH=6.5; 24 h; aq. phosphate bufferEnzymatic reaction; 3: With water; sodium hydroxide in methanol T=20°C; 1 h; optical yield given as percent eeenantioselective reaction;

glutaryl acylase in methanol; water T=25°C; pH=7.0; 8 h; Title compound not separated from byproducts;

sodium hydroxide; glutaryl-7-aminocephalosporanic acid acylase in water T=25°C; pH=8.0; Enzymatic reaction; Enzyme kinetics;