4,5-二溴-2,7-二叔丁基-9,9-二甲基呫吨合成路线 （共 8 条）
反应条件
bromine; iron in chloroform T=20°C;
参考文献
Chang, Kyoung-Jin; An, Young-Jae; Uh, Hyounsoo; Jeong, Kyu-Sung
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6556 - 6563
反应条件
bromine; iron in tetrachloromethane 26 h; Ambient temperature; Yield given;
参考文献
Nowick, James S.; Ballester, Pablo; Ebmeyer, Frank; Rebek Jr., Julius
Journal of the American Chemical Society, 1990 , vol. 112, # 24 p. 8902 - 8906
反应条件
1: 58 percent / FeCl3 / CH2Cl2 / 1.) from 0 deg C to RT, 3 h, 2.) 15 h 2: bromine / CCl4 / 1.) from 0 deg C to RT, 3 h, 2.) 23 h 3: Fe, bromine / CCl4 / 26 h / Ambient temperature View Scheme
参考文献
Nowick, James S.; Ballester, Pablo; Ebmeyer, Frank; Rebek Jr., Julius
Journal of the American Chemical Society, 1990 , vol. 112, # 24 p. 8902 - 8906
反应条件
1: 96 percent / toluene / 1.) from 0 deg C to RT, 3 h, 2.) 14 h 2: 58 percent / FeCl3 / CH2Cl2 / 1.) from 0 deg C to RT, 3 h, 2.) 15 h 3: bromine / CCl4 / 1.) from 0 deg C to RT, 3 h, 2.) 23 h 4: Fe, bromine / CCl4 / 26 h / Ambient temperature View Scheme
参考文献
Nowick, James S.; Ballester, Pablo; Ebmeyer, Frank; Rebek Jr., Julius
Journal of the American Chemical Society, 1990 , vol. 112, # 24 p. 8902 - 8906
反应条件
1: 4,5-dibromo-2,7-di-tert-butyl-9,9-dimethylxanthene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: chloro-diphenylphosphine in tetrahydrofuran; hexane T=-78 - 25°C;
参考文献
Johns, Adam M.; Sakai, Norio; Ridder, Andre; Hartwig, John F.
Journal of the American Chemical Society, 2006 , vol. 128, # 29 p. 9306 - 9307
反应条件
1: With n-butyllithium in tetrahydrofuran T=-60°C; 2 h; 2: in toluene T=-60 - 20°C;
参考文献
Celanese GmbH
Patent: US6342605 B1, 2002 ;
Location in patent: Page column 6 ;
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran 1.2: 83 percent / hydrochloric acid / hexane; tetrahydrofuran 2.1: 83 percent / H2SO4; NaN3 / CHCl3 / 2.5 h / 20 - 51 °C View Scheme
参考文献
Chang, Kyoung-Jin; An, Young-Jae; Uh, Hyounsoo; Jeong, Kyu-Sung
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6556 - 6563
反应条件
1: 4,5-dibromo-2,7-di-tert-butyl-9,9-dimethylxanthene With n-butyllithium in tetrahydrofuran; hexane 2: carbon dioxide With hydrogenchloride in tetrahydrofuran; hexane
参考文献
Chang, Kyoung-Jin; An, Young-Jae; Uh, Hyounsoo; Jeong, Kyu-Sung
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6556 - 6563
