5-乙酰氨基-7,8,9-O-三乙酰基-2,6-脱水-4-叠氮-3,4,5-三脱氧-D-甘油-D-半乳-2-壬烯酸甲酯合成路线 （共 44 条）
反应条件
1: 72 percent / hydrogen, acetic acid / 10percent Pd/C / methanol; toluene / 1 h 2: Amberlite IRA-400(OH-) / methanol / 3 h / Ambient temperature View Scheme
参考文献
Shidmoossavee, Fahimeh S.; Watson, Jacqueline N.; Bennet, Andrew J.
Journal of the American Chemical Society, 2013 , vol. 135, # 36 p. 13254 - 13257
反应条件
hydrogen in ethanol T=20°C; 9 h;
参考文献
Nishino, Reiko; Ikeda, Kiyoshi; Hayakawa, Takuya; Takahashi, Tadanobu; Suzuki, Takashi; Sato, Masayuki
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 7 p. 2418 - 2427
反应条件
sodium methylate in methanol T=21°C; 2.5 h;
参考文献
Chandler, Malcolm; Bamford, Mark J.; Conroy, Richard; Lamont, Brian; Patel, Bina; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 9 p. 1173 - 1180
反应条件
1: zinc; ammonium chloride / water / 20 - 30 °C 2: sodium acetate; bromocyane / methanol / 15 - 20 °C View Scheme
参考文献
CIPLA LIMITED
Patent: US2011/257418 A1, 2011 ;
