2-(吡咯烷-1-基羰基)哌啶合成路线 (共 5 条)
反应条件
1: SOCl2 / CH2Cl2 / 24 h / Ambient temperature 2: CH2Cl2 / -5 °C View Scheme
参考文献
Vecchietti; Giordani; Giardina; Colle; Clarke
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 397 - 403
反应条件
1: NaOH / H2O / 0 °C 2: SOCl2 / CH2Cl2 / 24 h / Ambient temperature 3: CH2Cl2 / -5 °C View Scheme
参考文献
Vecchietti; Giordani; Giardina; Colle; Clarke
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 397 - 403
反应条件
in dichloromethane T=-5°C; Yield given;
参考文献
Vecchietti; Giordani; Giardina; Colle; Clarke
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 397 - 403
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=30°C; 3 h;
参考文献
Vecchietti; Giordani; Giardina; Colle; Clarke
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 397 - 403
反应条件
1: 71 percent / LiAlH4 / tetrahydrofuran / 3 h / 30 °C 2: K2CO3 / CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Vecchietti; Giordani; Giardina; Colle; Clarke
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 397 - 403