(R)-(+)-1-苄基丙三醇合成路线 （共 40 条）
反应条件
sodium hydride
1) 30 min, r. t., THF, 2) 12 h, reflux; Yield given;
参考文献
Weber, Edwin
Liebigs Annalen der Chemie, 1983 , # 5 p. 770 - 801
反应条件
lithium bromide; lithium tert-butylate
1.) tert-Butanol, reflux, 2.) reflux, ca. 12 d; Yield given. Multistep reaction;
参考文献
Miyazaki, Takeshi; Yanagida, Shozo; Itoh, Akira; Okahara, Mitsuo
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 7 p. 2005 - 2009
反应条件
lithium bromide; lithium tert-butylate
1.) xylene, t-BuOH, 2.) xylene, t-BuOH, 85-95 deg C, 2 d; Yield given. Multistep reaction;
参考文献
Miyazaki, Takeshi; Yanagida, Shozo; Itoh, Akira; Okahara, Mitsuo
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 7 p. 2005 - 2009
反应条件
sodium hydride in tetrahydrofuran
12 h; Heating;
参考文献
Weber, Edwin
Liebigs Annalen der Chemie, 1983 , # 5 p. 770 - 801
反应条件
lithium bromide; lithium tert-butylate
1.) t-BuOH, 2.) t-BuOH, reflux, 10 d; Yield given. Multistep reaction;
参考文献
Miyazaki, Takeshi; Yanagida, Shozo; Itoh, Akira; Okahara, Mitsuo
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 7 p. 2005 - 2009
反应条件
1: 1.) NaH / 1.) THF, RT, 30 min, 2.) THF, RT, 3 h
2: 94 percent / LiAlH4 / tetrahydrofuran / 10 h / Heating
View Scheme
参考文献
Bartsch, Richard A.; Cason, Victor C.; Czech, Bronislaw P.
Journal of Organic Chemistry, 1989 , vol. 54, # 4 p. 857 - 860
参考文献
Czech, Bronislaw; Kang, Sang Ihn; Bartsch, Richard A.
Tetrahedron Letters, 1983 , vol. 24, # 5 p. 457 - 460
反应条件
4-(N,N-dimethlyamino)pyridine
参考文献
Williams, John R.
Steroids, 1995 , vol. 60, # 4 p. 333 - 336
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane
T=0 - 20°C;
参考文献
Martin, Stephen F.; Josey, John A.
Tetrahedron Letters, 1988 , vol. 29, # 30 p. 3631 - 3634
反应条件
1: 30 percent / Py / CHCl3 / 48 h / 20 °C
2: 79 percent / Et3N / benzene / 1 h / Heating
View Scheme
参考文献
Takahashi, Toshihiro; Ido, Tatsuo; Nagata, Shinji; Iwata, Ren
Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 9 p. 943 - 969
