2-甲氧基苯氧基乙酸乙酯合成路线 （共 11 条）
反应条件
1: 2-methoxy-phenol With potassium carbonate in acetone T=20°C; 0.25 h; Inert atmosphere; 2: ethyl bromoacetate in acetone T=0°C; 8 h; Inert atmosphereReflux;
参考文献
Chemistry - A European Journal, , vol. 17, # 49 p. 13877 - 13882
反应条件
toluene-4-sulfonic acid T=20°C;
参考文献
Medicinal Chemistry Research, , vol. 19, # 1 p. 33 - 57
参考文献
Chemische Berichte, , vol. 27, p. 2799
反应条件
1: 65 percent / hydrazine hydrate / ethanol / 12 h / Heating 2: benzene / 5 h 3: 2 N NaOH / H2O / 3 h / Heating View Scheme
参考文献
Husain, M. I.; Amir, Mohd; Singh, Eira
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 251 - 254
参考文献
Auwers; Haymann
Chemische Berichte, 1894 , vol. 27, p. 2799
Full Text Show Details
v. Walther
Journal fuer Praktische Chemie (Leipzig), 1902 , vol. <2> 65, p. 480
反应条件
1.1: diisopropylamine; n-butyllithium / tetrahydrofuran; hexane / 0.58 h / -78 - 0 °C / |Inert atmosphere 1.2: 0.25 h / -78 °C / |Inert atmosphere 2.1: tetrahydrofuran; diethyl ether / 5 h / 0 - 50 °C / |Inert atmosphere; |Schlenk technique 3.1: sodium hydroxide; sodium sulfate / 2 h / |Milling; |Inert atmosphere View Scheme
参考文献
Green Chemistry, , vol. 15, # 1 p. 160 - 166
反应条件
hydrazine hydrate in ethanol 12 h; Heating;
参考文献
Husain, M. I.; Amir, Mohd; Singh, Eira
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 251 - 254
Title/Abstract Full Text Show Details
Husain, M. I.; Amir, Mohd.
Journal of the Indian Chemical Society, 1986 , vol. 63, p. 317 - 319
反应条件
potassium hydroxide in methanol; water T=20°C; Inert atmosphere;
参考文献
Buendia, Julien; Mottweiler, Jakob; Bolm, Carsten
Chemistry - A European Journal, 2011 , vol. 17, # 49 p. 13877 - 13882
反应条件
1: lithium diisopropyl amide / tetrahydrofuran / -78 °C
2: sodium tetrahydroborate / tetrahydrofuran; water
3: palladium on activated charcoal; hydrogen / methanol
4: 4-acetylamino 2,2,6,6-tetramethylpiperidin-N-oxyl; oxygen; nitric acid; hydrogenchloride / water; acetonitrile / 24 h / 45 °C / |High pressure; |Sealed tube
View Scheme
参考文献
Rahimi, Alireza; Azarpira, Ali; Kim, Hoon; Ralph, John; Stahl, Shannon S.
Journal of the American Chemical Society, 2013 , vol. 135, # 17 p. 6415 - 6418
反应条件
1: potassium hydroxide / methanol; water / 20 °C / Inert atmosphere
2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Buendia, Julien; Mottweiler, Jakob; Bolm, Carsten
Chemistry - A European Journal, 2011 , vol. 17, # 49 p. 13877 - 13882
