3,4-二甲氧基-N-甲基苯乙胺 盐酸盐合成路线 (共 8 条)
反应条件
1: With hydrogen; 5-palladium/activated carbon in water T=75°C; 16 - 40 h; 2: With hydrogen; AlCl3, aluminium chloride in water P=2585.81 Torr; 20 - 105 h; 3: With hydrogenchloride; sodium hydroxide Product distribution / selectivity; more than 3 stages;
参考文献
ALBANI, Davide; Arosio, Roberto; Merli, Valeriano
Patent: US2009/171110 A1, 2009 ;
Location in patent: Page/Page column 6 ;
反应条件
1: With AlCl3, aluminium chloride in water T=85°C; 2: With hydrogen; 5-palladium/activated carbon in water T=85°C; P=2585.81 Torr; 36 h; 3: With hydrogenchloride; sodium hydroxide Product distribution / selectivity; more than 3 stages;
参考文献
ALBANI, Davide; Arosio, Roberto; Merli, Valeriano
Patent: US2009/171110 A1, 2009 ;
Location in patent: Page/Page column 5 ;
反应条件
1: With hydrogen; 5-palladium/activated carbon in water T=75°C; 24 h; 2: With hydrogenchloride; hydrogen in water 19 - 96 h; Product distribution / selectivity;
参考文献
US2009/171110 A1, ;
Page/Page column 6-7 ;
反应条件
1: With hydrogen; ammonium chloride; AlCl3, aluminium chloride; palladium 10 on activated carbon in water T=62 - 70°C; P=2585.81 Torr; 42 h; 2: With 4.5-0.5 Pd-Ru/C in water 3: With sodium hydroxide; ammonium chloride Product distribution / selectivity; more than 3 stages;
参考文献
US2009/171110 A1, ;
Page/Page column 7-8 ;
反应条件
1: With hydrogen; ammonium chloride; AlCl3, aluminium chloride; 5-palladium/activated carbon in water T=65 - 85°C; P=2585.81 Torr; 42 h; 2: With sodium hydroxide in water; toluene pH=12; 3: With hydrogenchloride in acetone T=5 - 15°C; Product distribution / selectivity;
参考文献
US2009/171110 A1, ;
Page/Page column 7 ;
反应条件
1: With hydrogen; palladium 10 on activated carbon in ethanol T=40 - 45°C; 2: With sodium hydroxide in water 3: With hydrogenchloride in isopropyl alcohol
参考文献
ALBANI, Davide; Arosio, Roberto; Merli, Valeriano
Patent: US2009/171110 A1, 2009 ;
Location in patent: Page/Page column 6 ;
反应条件
sodium tris(acetoxy)borohydride in 1,2-dichloro-ethane
T=20°C; 12 h;
参考文献
Mermerian, Ara H.; Fu, Gregory C.
Angewandte Chemie - International Edition, 2005 , vol. 44, # 6 p. 949 - 952
反应条件
1: PPA / 3 h / 60 °C
2: 60 percent / KMnO4, 18-crown-6 / 0.5 h / Ambient temperature
View Scheme
参考文献
Venkov, Atanas P.; Ivanov, Ilian I.
Tetrahedron, 1996 , vol. 52, # 37 p. 12299 - 12308