反应条件
1: triethylamine / dichloromethane / 0.5 h / 0 - 20 °C / |Inert atmosphere 2: polyphosphoric acid / 2 h / 120 °C / |Inert atmosphere 3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / 1,4-dioxane / |Inert atmosphere; |Reflux View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; AEBI, Johannes; AMREIN, Kurt; CHEN, Wenming; HORNSPERGER, Benoit; KUHN, Bernd; LIU, Yongfu; MAERKI, Hans P.; MAYWEG, Alexander V.; MOHR, Peter; TAN, Xuefei; WANG, Zhanguo; ZHOU, Mingwei
Patent: WO2013/79452 A1, 2013 ;