1: bromo-difluoroacetic acid,ethyl ester With zinc in triglyme (triethylene glycol dimethyl ether) T=20 - 30°C; 0.25 h; Inert atmosphereSonication; 2: With copper (I) cyanide in triglyme (triethylene glycol dimethyl ether) T=20°C; 0.5 h; 3: 2-(bromomethyl)propenoic acid ethyl ester in tetrahydrofuran; triglyme (triethylene glycol dimethyl ether) T=20°C; 44 h;

1: With lithium hydroxide hydrate in tetrahydrofuran T=0°C; 3 h; 2: pH=1; Acidic conditions;